Gigantism or excessive growth in height is due to excessive production of growth hormone from the adenoma of the anterior pituitary gland before epiphyseal closure. Height becomes 7-8 feet.
Skeletal muscles may be powerfully developed but later pituitary insufficiency may occur with
associated muscular weakness.
There may be hypertension due to excessive growth hormone,
The X-ray skull: shows an enlargement of sella
Refer to Acromegaly for details