PROSTATE CARCINOMA

CLINICAL FEATURES

Urinary flow obstruction.

Acute urinary retention may occur if the gland suddenly enlarges in size due to infection or congestion.

Hematuria due to urethral bleeding may be the presenting symptom.

On per rectal examination prostate is hard and the medium sulcus is obliterated.

Signs of metastasis such as bone pain

Investigations

The spread of the tumour is often associated with increased serum prostate-specific antigen (PSA ) which acts as a tumour marker.

Serum PSA

Bone scan

X-rays of bone

CXR

LFT

• CT scan of abdomen: to look for involvement of regional lymph node.

Management

Radical prostatectomy

Radiotherapy

Androgen deprivation