Atrial fibrillation

 

Atrial Fibrillation

Symptoms

  • Palpitations, which are sensations of a racing, uncomfortable, irregular heartbeat or a flip-flopping in your chest
  • Weakness
  • Reduced ability to exercise
  • Fatigue
  • Lightheadedness
  • Dizziness
  • Shortness of breath
  • Chest pain

Atrial fibrillation may be:

  • Occasional.
  • Persistent.
  • Long-standing persistent.
  • Permanent.
  • Fast  AF
  • Slow AF

Possible causes of atrial fibrillation

  • High blood pressure
  • Heart attack
  • Coronary artery disease
  • Abnormal heart valves
  • Heart defects you’re born with (congenital)
  • An overactive thyroid gland or other metabolic imbalance
  • Exposure to stimulants, such as medications, caffeine, tobacco or alcohol
  • Sick sinus syndrome — improper functioning of the heart’s natural pacemaker
  • Lung diseases
  • Previous heart surgery
  • Viral infections
  • Stress due to surgery, pneumonia, or other illnesses
  • Sleep apnea

Risk factors

  • Age. The older you are, the greater your risk of developing atrial fibrillation.
  • Heart disease. Anyone with heart disease — such as heart valve problems, congenital heart disease, congestive heart failure, coronary artery disease, or a history of heart attack or heart surgery — has an increased risk of atrial fibrillation.
  • High blood pressure.
  • Other chronic conditions. such as thyroid problems, sleep apnea, metabolic syndrome, diabetes, chronic kidney disease or lung disease
  • Alcohol Xs. Binge drinking may put you at an even higher risk.
  • Obesity
  • Family history

Complications

Sometimes atrial fibrillation can lead to the following complications:

  • Stroke.
  • Heart failure.

Investigations

  • Electrocardiogram
  • Holter monitor.
  • Echocardiogram.
  • Blood tests (FBE, U&E, TSH, Calcium, Magnesium)
  • Chest X-ray.

Management

Rate control

Metoprolol

Bisoprolol

Atenolol

Digoxin

Verapamil

AV node ablation

Permanent pacemaker

Rhythm control

Flecainide

Sotalol

Amiodarone

Electrical cardioversion

Catheter ablation

Anticoagulation

The NHFA’s AF guidelines have simplified estimating stroke risk by removing female sex from the risk calculator, leaving CHA2DS2-VA (Congestive heart failure, Hypertension, Age >75 years [2 points], Diabetes, Stroke/transient ischaemic attack [2 points/1 point respectively], Vascular disease, Age >65 years).9 This has resulted in the following recommendations for both sexes:

  • CHA2DS2-VA = 0: Oral anticoagulants (OACs) are not recommended
  • CHA2DS2-VA = 1: OACs should be considered
  • CHA2DS2-VA = 2: OACs are recommended.

Examples

Warfarin

Apixaban

Pradaxa

Xarelto

 

 

 

 

 

 

 

 

 

 

 

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