Sarcoidosis
Sarcoidosis
Multisystem inflammatory disease of unknown cause characterized by non-caseating granuloma.
Typically presents with lung granuloma in a young adult.
Clinical features
Tiredness,
Malaise
Weight loss
Arthralgia. 1
Gradual onset of progressive exertional dyspnoea
Dry cough.
Non-respiratory manifestations of sarcoidosis
Fever and malaise
Erythema nodosum
Lupus pernio (blue red nodules on the nose, face, and/or hands) • Scar infiltration
Enlarged lacrimal glands
Hypopyon
Uveitis
Arthralgia
Arrhythmias
Heart failure
Pericardial effusion
Cranial and/or peripheral nerve palsies
Seizures
Hypercalcaemia
Renal stones
Lymphadenopathy
Hepatosplenomegaly
Investigation
Bilateral hilar lymphadenopathy on CXR –
Serum ACE
Management
Refer to a respiratory physician
