MULTIPLE ENDOCRINE NEOPLASIA

(MEN 1 AND MEN II)

Simultaneous occurrence of tumours involving a number of endocrine glands is called MEN.

MEN I (Werner’s syndrome)

1 . Primary hyperparathyroidism

2. Functioning pituitary tumours

3. Pancreatic tumours (e.g. insulinoma,
gastrinoma)

MEN II (Sipple’s syndrome)

1 . Primary hyperparathyroidism

2. Medullary carcinoma of the thyroid

3 . Phaeochromocytoma