Sarcoidosis

 

Sarcoidosis

Multisystem inflammatory disease of unknown cause characterized by non-caseating granuloma.

Typically presents with lung granuloma in a young adult.

Clinical features

Tiredness,

Malaise

Weight loss

Arthralgia. 1

Gradual onset of progressive exertional dyspnoea

Dry cough.

Non-respiratory manifestations of sarcoidosis

Fever and malaise

Erythema nodosum

Lupus pernio (blue red nodules on the nose, face, and/or hands) • Scar infiltration
Enlarged lacrimal glands

Hypopyon

Uveitis

Arthralgia

Arrhythmias

Heart failure

Pericardial effusion

Cranial and/or peripheral nerve palsies

Seizures

Hypercalcaemia

Renal stones

Lymphadenopathy

Hepatosplenomegaly

Investigation

Bilateral hilar lymphadenopathy on CXR –

Serum ACE

Management

Refer to a respiratory physician

 

 

 

 

 

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